EPILEPSY AND COGNITION LAB
Epilepsy is more than just seizures.
Children and adults with epilepsy often experience problems with intellectual development, learning, memory, and attention – symptoms that can sometimes be even more disabling than seizures. In our lab, we study neural networks that mediate these cognitive functions in developing and mature brains. By understanding the physiology of these networks and how they are disrupted by epileptic activity, we work toward targeted treatments that aim not only to stop seizures, but also to address cognitive comorbidities.
EPILEPSY AND MEMORY
We use memory tasks and large-scale neural recordings in behaving rodents to understand the interplay between epileptic activity and memory. We also use closed loop technologies to perturb these neural networks with the goal of altering memory function.
We perform multi-cortical neurophysiologic recordings in wild type neonatal and juvenile rodents as well as those harboring mutations associated with epilepsy, autism, and intellectual disability to understand the unique features of these neurodevelopmental disorders.
DEVICES AND COMPUTATION FOR EPILEPTIC NETWORKS
We develop computational approaches to interictal epileptic networks using intracranial EEG data from patients with epilepsy, and leverage advanced neural interface devices to gain higher spatiotemporal resolution data from these networks.