EPILEPSY AND MEMORY
We use memory tasks and large-scale neural recordings in behaving rodents to understand the interplay between epileptic activity and memory. We also use closed loop technologies to perturb these neural networks with the goal of altering memory function.
We perform multi-cortical neurophysiologic recordings in wild type neonatal and juvenile rodents as well as those harboring mutations associated with epilepsy, autism, and intellectual disability to understand the unique features of these neurodevelopmental disorders.
DEVICES AND COMPUTATION FOR EPILEPTIC NETWORKS
We develop computational approaches to interictal epileptic networks using intracranial EEG data from patients with epilepsy, and leverage advanced neural interface devices to gain higher spatiotemporal resolution data from these networks.